HSip-1 (Cyclen-AF-Cu; Hydrogen Sulfide imaging probe-1) is a sensitive hydrogen sulfide (H2S) fluorescent probe that displays a selective turn-on fluorescence response to sulfide anion (Ex/Em = 491/516 nm), but not GSH, L-Cys, DL-Hcy, 2-ME, DTT, SCN-, Na2SO3, Na2S2O3, or sodium ascorbate. HSip-1 is not membrane-permeable and is commonly employed for detecting H2S in media/buffers, cell lysates, blood, physiological fluids and tissue homogenates. HSip-1 is commonly used in the range from 1-100 μM depending on the H2S concentrations in samples, optimal probe concentration needs to be titred.
Sensitive and selective hydrogen sulfide (H2S) fluorescent probe.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Cytoprotective effects of hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonists are mediated by intracellular sulfane sulfur
MedChemComm, 5(10), 1577-1583 (2014)
Development of a highly selective fluorescence probe for hydrogen sulfide
Journal of the American Chemical Society, 133(45), 18003-18005 (2011)
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