SML0817

Pivmecillinam

≥98% (HPLC)

• Sinónimos: Amdinocillin pivoxil
• Fórmula empírica (notación de Hill): C₂₁H₃₃N₃O₅S
• Número de CAS: 32886-97-8
• Peso molecular: 439.57
• Número CE: 251-276-6
• Número MDL: MFCD00865080
• Código UNSPSC: 51111800
• ID de la sustancia en PubChem: 329825603
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D +215 to +245°, c = 1 in ethanol
• color: white to beige
• solubilidad: DMSO: 5 mg/mL, clear (warmed)
• temp. de almacenamiento: −20°C
• cadena SMILES: CC1(C)[C@H](C(OCOC(C(C)(C)C)=O)=O)N2C([C@](/N=C/N3CCCCCC3)([H])[C@@]2([H])S1)=O
• InChI: 1S/C21H33N3O5S/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23/h12,14-15,17H,6-11,13H2,1-5H3/b22-12+/t14-,15+,17-/m1/s1
• Clave InChI: NPGNOVNWUSPMDP-UTEPHESZSA-N

Descripción

Aplicación

Pivmecillinam has been used to test its efficacy as a breast cancer stem cells (CSCs) targeting agent.[1]

Acciones bioquímicas o fisiológicas

Pivmecillinam is a β-lactam antibiotic and a pivaloyl-containing pro-drug.[2] It belongs to the class of amidinopenicillin.[3] Pivmecillinam is an oral anti-microbial agent that can be considered for treating E. coli urinary tract infection (UTI).[4]

Pivmecillinam is a gram negative antibiotic, and inhibitor of penicillin-binding protein 2 (PBP2).

Pivmecillinam is a gram negative antibiotic, and inhibitor of penicillin-binding protein 2 (PBP2). Pivmecillinam has been shown to have synergistic effects with several antibiotics including novobiocin and rifampin in gram negative bacteria.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable