SAB5701303

Anti- HuR/ELAVL1 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41
• clone: monoclonal
• application: WB
• species reactivity: mouse, rat, human
• technique(s): western blot: 1:500-1:2000

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• species reactivity: mouse, rat, human
• concentration: 0.6 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q15717
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ELAVL1(1994)

Descripción

General description

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

Immunogen

A synthesized peptide derived from human HuR/ELAVL1.

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable