CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic-receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.
Inmunógeno
Synthetic peptide near the C-terminus of human CD169 protein.
Características y beneficios
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Forma física
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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