SAB4503974

Anti-phospho-PLK1 (pThr²¹⁰) antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.43

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 68 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: P53350
• UniProt accession no.: P53350
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr210)
• Gene Information: human ... PLK1(5347)

Descripción

General description

Human polo-like kinase 1 (PLK1) is a serine/threonine kinase, that is located on human chromosome 16p12.

Immunogen

The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210.

Immunogen Range: 176-225

Biochem/physiol Actions

Polo-like kinase 1 (PLK1) plays an important role in the functional maturation of mitotic centrosomes. It actively participates in the development of the cell cycle. This gene is considered as an important therapeutic target as it is overexpressed in several cancer types.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable