SAB4300160

Anti-phospho-BCR (pTyr¹⁷⁷) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-ALL antibody produced in rabbit, Anti-BCR-ABL1 antibody produced in rabbit, Anti-BCR1 antibody produced in rabbit, Anti-CML antibody produced in rabbit, Anti-breakpoint cluster region antibody produced in rabbit
• MDL number: MFCD02686065
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~210 kDa
• species reactivity: mouse, human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (P-F-YP-V-N)
• NCBI accession no.: NP_004318.3
• UniProt accession no.: P11274
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr177)
• Gene Information: human ... BCR(613)

Descripción

Immunogen

Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N), according to the protein BCR.

Features and Benefits

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Target description

GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable