SAB4300045

Anti-phospho-NBN (pSer³⁴³) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-AT-V1 antibody produced in rabbit, Anti-AT-V2 antibody produced in rabbit, Anti-ATV antibody produced in rabbit, Anti-FLJ10155 antibody produced in rabbit, Anti-nibrin antibody produced in rabbit
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: ~95 kDa
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (S-L-SP-Q-G)
• Nº de acceso NCBI: NP_002476.2
• Nº de acceso UniProt: O60934
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer343)
• Información sobre el gen: human ... NBN(4683)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G), according to the protein NBN.

Características y beneficios

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Descripción de destino

Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable