S3884
Sauvagine
≥97% (HPLC)
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About This Item
Fórmula empírica (notación de Hill):
C202H346N56O63S
Número de CAS:
Peso molecular:
4599.31
Número MDL:
Código UNSPSC:
12352200
NACRES:
NA.32
Ensayo
≥97% (HPLC)
temp. de almacenamiento
−20°C
Clave InChI
ILCVKEBXPLEGOY-ZLFMSJRASA-N
Amino Acid Sequence
Glp-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
Descripción general
Acciones bioquímicas o fisiológicas
A peptide related to CRF and urotensin 1 that was first isolated from the skin of the frog Phyllomedusa sauvagei. Potent releaser of ACTH and β-endorphin from the anterior pituitary.
Otras notas
Lyophilized from 0.1% TFA in H2O
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Takeshi Nakamura et al.
American journal of physiology. Heart and circulatory physiology, 296(2), H325-H332 (2008-12-09)
Urocortin 3 (Ucn3) is a new member of the corticotropin-releasing factor (CRF) peptide family and is considered to be a specific and endogenous ligand for CRF type 2 receptors (CRF2Rs). The presence of CRF(2)Rs has been reported in the nucleus
Javier Santos et al.
Psychoneuroendocrinology, 33(9), 1248-1256 (2008-08-12)
Previously, we showed that corticotropin-releasing factor (CRF) injected i.p. mimicked epithelial responses to stress, both stimulating ion secretion and enhancing permeability in the rat colon, and mast cells were involved. However, the ability of CRF-sensitive mucosal/submucosal loops to regulate intestinal
Eric Gutknecht et al.
Journal of neurochemistry, 104(4), 926-936 (2007-11-03)
Endogenous expression of the corticotropin-releasing factor type 2a receptor [CRF2(a)] but not CRF2(b) and CRF2(c) was observed in higher passage cultures of human Y79 retinoblastoma cells. Functional studies further demonstrated an increase in CRF2(a) mRNA and protein levels with higher
Kostas Gkountelias et al.
Molecular pharmacology, 78(4), 785-793 (2010-07-29)
Family B of G protein-coupled receptors (GPCRs) is composed of receptors that bind peptides, such as secretin, glucagon, parathyroid hormone, and corticotropin releasing factor (CRF), which play critical physiological roles. These receptors, like all GPCRs, share a common structural motif
T Renda et al.
Archives of histology and cytology, 52 Suppl, 317-323 (1989-01-01)
The authors present an overview of the main amphibian peptide families mainly derived from the skin and mostly discovered by Erspamer and his associates. The studies of the peptides do not only promote the understanding of their chemical, metabolical and
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