R4780

RACK1 human

recombinant, expressed in E. coli, >90% (SDS-PAGE), buffered aqueous solution

• Sinónimos: Receptor for activated protein kinase C
• Código UNSPSC: 12352200
• NACRES: NA.32

Propiedades

• recombinante: expressed in E. coli
• Ensayo: >90% (SDS-PAGE)
• Formulario: buffered aqueous solution
• mol peso: 37 kDa
• Nº de acceso UniProt: P63244
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... GNB2L1(10399)

Descripción

Acciones bioquímicas o fisiológicas

RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth.

RACK1 is an intracellular receptor protein that binds activated members of the protein kinase C family.

Forma física

Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)