PRS4553

Anti-Unc93b antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-Unc-93 homolog B1 (C. elegans), Anti-Unc93b1
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: rat, human, mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q9H1C4
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... UNC93B1(81622)

Descripción

General description

Unc93b (unc-93 homolog B1) is a multiple membrane-spanning protein, that is located in the endoplasmic reticulum. It is mainly present in the heart and also highly expressed in dendritic cells and macrophages. It is located on chromosome 11q13.

Immunogen

a 19 amino acid peptide from near the amino-terminus of human Unc93b.

Biochem/physiol Actions

Unc93b (unc-93 homolog B1) plays an important role in controlling the activation of TLRs (toll-like receptors). It also participates in the localization of TLR3 (toll-like receptor 3) to the surface of cell.

Linkage

The action of this antibody can be blocked using blocking peptide SBP4553.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable