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MAK126

Sigma-Aldrich

Bilirubin Assay Kit

sufficient for 180 colorimetric tests

Sinónimos:

Hematoidin Assay Kit

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1 KIT
US$ 488,00

US$ 488,00

PRECIOS SIN IMPUESTOS NACIONALES
Normalmente se envía en 2 semanas.
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1 KIT
US$ 488,00

About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

US$ 488,00

PRECIOS SIN IMPUESTOS NACIONALES
Normalmente se envía en 2 semanas.
Solicitar un pedido a granel

uso

sufficient for 180 colorimetric tests

método de detección

colorimetric

enfermedades relevantes

hematological disorder; gastrointestinal diseases

temp. de almacenamiento

2-8°C

Categorías relacionadas

Descripción general

Bilirubin, also known as hematoidin, is a degradation product formed as a result of heme catabolism in the liver. Bilirubin circulates in the blood stream as either the unconjugated insoluble form (indirect bilirubin) or the soluble glucuronide-conjugated form (direct bilirubin). Conjugated bilirubin moves from the bile canaliculi of the liver to the gall bladder where it is excreted into the small intestine during digestion. High levels of bilirubin can result in jaundice and may indicate liver disease, blood disorders, or blockage of the bile ducts.

Aplicación

Bilirubin Assay Kit has been used to measure the total bilirubin concentration in samples.[1][2]

Características y beneficios

Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.

Idoneidad

Suitable for the detection of of both total and conjugated bilirubin in serum and plasma samples.

Principio

This assay, based on the Jendrassik-Grof method, utilizes the reaction of bilirubin with diazotized sulfanilic acid resulting in a colorimetric product measured at 530 nm, proportionate to the bilirubin present in the sample. This assay kit measures both total and conjugated bilirubin.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
126CE12A23
126CE12A23
126CE07A16
126CE05A09
126CE05A10

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Questions

1–7 of 7 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can you please confirm me if these assays works with mouse samples?

    1 answer

    1. All three kits have been used with mouse samples.

      Helpful?

  4. What is a typical absorbance range for the 5 mg/dL standard in the MAK126 Bilirubin Assay Kit?

    1 answer

    1. The OD that represents 5mg/dL bilirubin was determined to be 0.52-0.56 during the development of the kit.

      Helpful?

  5. Does this kit work with urine samples?

    1 answer

    1. Kit MAK126 has not been tested on urine samples, so it is not something that can be guaranteed, but it is likely that urine would be okay as long as the concentration falls within the detection range of the kit. Bilirubin does not typically contain urine, so it may not exhibit a response from the kit unless the urine in question comes from a subject with a certain liver condition.

      Helpful?

  6. Can I use the Bilirubin Assay Kit (MK126) to do Bilirubin Assay for mouse?

    1 answer

    1. This Billirubin Assay is not species specific. It has not been tested specifically on mouse serum, however there is no reason to suspect that this kit would not be suitable. Please see the links below to review publications utilizing this product with mouse serum:
      https://doi.org/10.3389/fphar.2018.00410
      https://doi.org/10.1152/ajpheart.00882.2014
      https://doi.org/10.1002/path.5685

      Helpful?

  7. Hola. Deseo medir bilirrubina total en una colección de sueros que se han mantenido congelados a -70ºC varios meses. Necesitaría saber si su kit es recomendable para estas muestras y la cantidad mínima de suero (humano) que se puede usar por reacción. Gcs

    1 answer

    1. Measurement of Total and Direct Bilirubin requires a total of 150 microliters of sample (50 microliters each for Total, Direct, and Sample Blank). Serum (frozen or fresh) is a suitable sample for use with the kit.

      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/254/564/mak126bul.pdf

      Helpful?

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