L2885

Lymphotoxin-β Receptor/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Sinónimos: TNF R-related protein, TNF RIII
• Número MDL: MFCD03100005
• Código UNSPSC: 51111800

Propiedades

• origen biológico: human
• recombinante: expressed in NSO cells
• Ensayo: >95% (SDS-PAGE)
• Formulario: lyophilized powder
• mol peso: monomer calculated mol wt 49.6 kDa; 70 kDa by SDS-PAGE (reducing) (due to glycosylation)
• envase: pkg of 100 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• técnicas: cell culture | mammalian: suitable
• impurezas: endotoxin, tested
• Nº de acceso UniProt: P36941
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... LTBR(4055)

Descripción

Acciones bioquímicas o fisiológicas

LTBR (lymphotoxin β receptor) is a receptor for LIGHT (tumor necrosis factor ligand superfamily member 14) and LT (lymphotoxin)-a1β2. It is present in the epithelial, stromal and myeloid cells. LTBR participates in lymphoid organ development and immune homeostasis. It is also involved in the lipopolysaccharide (LPS)-mediated expression of IL (interleukin)-8.[1]

Forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Nota de análisis

The biological activity is measured by the ability of the immobilized LTβR/Fc to bind LTα2/β1 and LTα1/β2 in a functional ELISA.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable