I7026

Anti-Insulin-like Growth Factor Binding Protein-4 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Sinónimos: Anti-IGFBP-4
• MDL number: MFCD01633492
• UNSPSC Code: 51111800
• conjugate: unconjugated
• application: ELISA (i); Neutral; WB
• clone: polyclonal
• species reactivity: human
• citations: 2
• technique(s): indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL

Propiedades

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P22692
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IGFBP4(3487)

Descripción

General description

Insulin-like growth factor binding protein-4 (IGFBP-4) is a 26kD (approx.) protein expressed highly in non-paranchymal cells of the liver. IGFBP-4 is also expressed in spleen, liver, lung, kidney, adrenal, testis, heart, brain cortex, stomach and hypothalamus. It has a pivotal role in protecting cells from overstimulation caused by IGFs or towards activating the alternate transmembrane signaling pathways that are inhibited by IGF exposure. Anti-Insulin-like Growth Factor Binding Protein 4(IGFBP-4) antibody can be used in western blotting. Goat anti-IGFBP-4 antibody reacts specifically with recombinant human IGFBP-4. The product has shown no cross-reactivity for recombinant human IGFBP-1, recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-5 and recombinant human IGFBP-6.

Specificity

By immunoblotting and ELISA, the antibody show no cross-reactivity with recombinant human IGFBP-2, recombinant human IGFBP-3, recombinant human IGFBP-1, recombinant human IGFBP-5, and recombinant human IGFBP-6.

Immunogen

purified, NSO-derived, recombinant human insulin-like growth factor binding protein 4.

Application

Anti-Insulin-like Growth Factor Binding Protein-4(IGFBP-4) antibody can be used in neutralization and indirect ELISA.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.