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H4525

Sigma-Aldrich

19-Hydroxytestosterone

≥98% (HPLC)

Sinónimos:

4-Androstene-17β,19-diol-3-one

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About This Item

Fórmula empírica (notación de Hill):
C19H28O3
Número de CAS:
2126-37-6
Peso molecular:
304.42
MDL number:
MFCD00198776
UNSPSC Code:
12352200

assay

≥98% (HPLC)

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CC[C@@H]2O

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
086H3887
062K0899

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P A Cole et al.
The Biochemical journal, 268(3), 553-561 (1990-06-15)
Aromatase is a cytochrome P-450 enzyme that catalyzes the conversion of androgens into oestrogens via sequential oxidations at the 19-methyl group. Despite intensive investigation, the mechanism of the third step, conversion of the 19-aldehydes into oestrogens, has remained unsolved. We
S Watanabe et al.
Endocrine journal, 41(4), 421-427 (1994-08-01)
19-Hydroxyandrogens are known to be an intermediary metabolite in the aromatizing reaction, though the physiological role of this compound has not yet been clarified. In this study, microsomes obtained from human corpus luteum were incubated with testosterone or 19-hydroxytestosterone (19-OHT)
Y S Moon et al.
Steroids, 39(4), 419-430 (1982-04-01)
In eight separate experiments, theca and granulosa were isolated from human follicles (5-25 mm in diameter), and their capacities to metabolize radiolabelled testosterone in 24 hour cultures were assessed. Theca metabolized testosterone primarily to androstenedione, however significant aromatization to estradiol-17
G Leschber et al.
Andrologia, 21(6), 529-534 (1989-11-01)
Subcutaneous treatment of immature male rats with an estrogen precursor, 19-hydroxy-testosterone (19-OHT), at a daily dose of 1 mg/animal for 14 days leads to a significant decrease in the weight of testis, ventral prostate and seminal vesicle. The peripheral levels
J I Raeside et al.
The Journal of endocrinology, 137(2), 281-289 (1993-05-01)
19-Hydroxytestosterone and 19-hydroxyandrostenedione have been identified as secretory products of the testes in the mature male domestic pig. Their isolation and identification were made by reverse-phase high-performance liquid chromatography and capillary gas chromatography-mass spectrometry (CGC-MS) of extracts from testicular vein

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