H3042

Hemopressin trifluoroacetate salt

≥98% (HPLC), powder

• Sinónimos: Hemopressin from rat, Hemopressin from rat brain, L-Prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-leucyl-L-seryl-L-histidine trifluoroacetate salt, Pro-Val-Asn-Phe-Lys-Phe-Leu-Ser-His trifluoroacetate salt
• Fórmula empírica (notación de Hill): C₅₃H₇₇N₁₃O₁₂ · xC₂HF₃O₂
• Número de CAS: 568588-77-2
• Peso molecular: 1088.26 (free base basis)
• Número MDL: MFCD19443861
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329815190
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to off-white
• solubilidad: H₂O: ≥2 mg/mL
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• cadena SMILES: OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]3CCCN3)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc4c[nH]cn4)C(O)=O
• InChI: 1S/C53H77N13O12.C2HF3O2/c1-30(2)22-37(47(71)65-42(28-67)51(75)64-41(53(77)78)25-34-27-56-29-58-34)60-49(73)39(24-33-16-9-6-10-17-33)61-46(70)36(18-11-12-20-54)59-48(72)38(23-32-14-7-5-8-15-32)62-50(74)40(26-43(55)68)63-52(76)44(31(3)4)66-45(69)35-19-13-21-57-35;3-2(4,5)1(6)7/h5-10,14-17,27,29-31,35-42,44,57,67H,11-13,18-26,28,54H2,1-4H3,(H2,55,68)(H,56,58)(H,59,72)(H,60,73)(H,61,70)(H,62,74)(H,63,76)(H,64,75)(H,65,71)(H,66,69)(H,77,78);(H,6,7)/t35-,36-,37-,38-,39-,40-,41-,42-,44-;/m0./s1
• Clave InChI: FXBODCREWDDYNR-DFZCIRLNSA-N

Descripción

Acciones bioquímicas o fisiológicas

Hemopressin is a novel endogenous hypotensive peptide and a CB1 inverse agonist.

Hemopressin is an endogenous hypotensive nonapeptide derived from hemoglobin. Hemopressin reduces appetite, acting as a cannabinoid CB1 inverse agonist. It blocks signaling by CB(1) receptors but not by other members of family A G protein-coupled receptors (including the closely related CB(2) receptors.

Características y beneficios

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable