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H0267

Sigma-Aldrich

Hemoglobin A0, Ferrous Stabilized human

lyophilized powder

Sinónimos:

Hemoglobin A0 Ferrous Stabilized, Hemoglobin-A0

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About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352202
eCl@ss:
42030116
NACRES:
NA.61

origen biológico

human

Nivel de calidad

Ensayo

97-100% (agarose gel electrophoresis)

Formulario

lyophilized powder

técnicas

immunofluorescence: suitable

solubilidad

H2O: soluble 20 mg/mL

idoneidad

suitable for electrophoresis and chromatography standard

Nº de acceso UniProt

temp. de almacenamiento

−20°C

Información sobre el gen

human ... HBB(3043)

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Descripción general

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).

Aplicación

Hemoglobin A0, ferrous stabilized human has been used:
  • as the non-fluorescent absorber in the preparation of tissue-mimicking phantoms
  • to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
  • to study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF

Hemoglobin A0 was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.

Acciones bioquímicas o fisiológicas

Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE.

Envase

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Reconstitución

When reconstituted with buffer, gives >85% ferrous hemoglobin.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Perry Edwards et al.
Scientific reports, 7(1), 12224-12224 (2017-09-25)
We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a
Ying-Chin Lin et al.
Sensors (Basel, Switzerland), 20(24) (2020-12-24)
Glycated hemoglobin (HbA1c) levels are an important index for the diagnosis and long-term control of diabetes. This study is the first to use a direct and label-free photoelectric biosensor to determine HbA1c using bacteriorhodopsin-embedded purple membranes (PM) as a transducer.
Vivide Tuan-Chyan Chang et al.
Neoplasia (New York, N.Y.), 11(4), 325-332 (2009-03-25)
Cervical cancer is the second most common female cancer worldwide. The ability to quantify physiological and morphological changes in the cervix is not only useful in the diagnosis of cervical precancers but also important in aiding the design of cost-effective
Screening and diagnosis for haemoglobin disorders
Prevention of Thalassaemias and Other Haemoglobin Disorders, 1 (2013)
Randi E Gislefoss et al.
Biopreservation and biobanking, 19(6), 525-530 (2021-10-07)
Background: During sampling and processing, blood samples can be affected by hemolysis. Information is lacking regarding hemolysis for biobank samples. There is a need for a method that can easily measure hemoglobin as an indicator of hemolysis in stored samples

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