G1876
L-Glutamic acid γ-ethyl ester
Sinónimos:
L-Glutamic acid 5-ethyl ester
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About This Item
Fórmula lineal:
C2H5OCOCH2CH2CH(NH2)COOH
Número de CAS:
Peso molecular:
175.18
Beilstein/REAXYS Number:
1725589
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
application(s)
peptide synthesis
storage temp.
−20°C
SMILES string
CCOC(=O)CC[C@H](N)C(O)=O
InChI
1S/C7H13NO4/c1-2-12-6(9)4-3-5(8)7(10)11/h5H,2-4,8H2,1H3,(H,10,11)/t5-/m0/s1
InChI key
XMQUEQJCYRFIQS-YFKPBYRVSA-N
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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D Manahan-Vaughan
Neuropharmacology, 37(12), 1459-1464 (1999-01-14)
Activation of group 1 metabotropic glutamate receptors (mGluRs) has been shown to facilitate the induction of tetanically evoked long-term potentiation in vivo, whereas group 2 mGluR antagonists inhibit long-term depression (LTD) in the CA1 region. LTD has not been successfully
Cristina Marchetti et al.
Experimental brain research, 164(3), 406-410 (2005-07-02)
This study examined whether activation of group I metabotropic glutamate receptors (mGluRs) could modulate synaptic inhibition of spinal motoneurons in the neonatal rat isolated spinal cord. Recurrent inhibitory postsynaptic potentials (IPSPs) generated by Renshaw cells were evoked via antidromic stimulation
Rebecca J Chapman et al.
The European journal of neuroscience, 26(8), 2257-2268 (2007-09-27)
We have explored the potential involvement of the three main classes of metabotropic glutamate receptor in the modulation of a spinal locomotor network using tadpoles of the anuran amphibian Xenopus laevis. Selective activation of group I receptors in Xenopus embryos
Jeong S Han et al.
Molecular pain, 2, 18-18 (2006-05-10)
The latero-capsular part of the central nucleus of the amygdala (CeLC) is the target of the spino-parabrachio-amygdaloid pain pathway. Our previous studies showed that CeLC neurons develop synaptic plasticity and increased neuronal excitability in the kaolin/carrageenan model of arthritic pain.
Vilen A Movsesyan et al.
Journal of neurotrauma, 23(2), 117-127 (2006-03-01)
The effects of group II mGluR activation by selective agonist (-)-2-oxa-4-aminobicyclo[3.1. 0]hexane-4,6-dicarboxylate (LY379268) were examined in a mouse model of controlled cortical impact (CCI)-induced brain injury and in primary neuronal/glial and neuronal cultures subjected to mechanical trauma. Systemic administration of
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