E6635

Ácido etilenodiaminotetraacético disodium salt dihydrate

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

• Sinónimos: EDTA disodium salt, EDTA-Na₂, Edatamil, Edetato disodium salt dihydrate, Etilenodiaminotetraacetato de disodio dihydrate, Sequestrene Na₂
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Número CAS: 6381-92-6
• Peso molecular: 372.24
• NACRES: NA.77
• PubChem Substance ID: 24894632
• UNSPSC Code: 12352107
• EC Number: 205-358-3
• Beilstein/REAXYS Number: 3900609

Propiedades

• grade: Sigma Grade
• Quality Segment: 200
• assay: 98.5-101.5%
• form: powder
• reaction suitability: reagent type: chelator
• technique(s): cell culture | plant: suitable
• mp: 248 °C (dec.) (lit.)
• solubility: H₂O: soluble, clear, colorless
• SMILES string: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• InChI key: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Descripción

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Application

Quelante de cationes divalentes. Inhibe las enzimas, como las metaloproteasas, que requieren cationes divalentes para ser activas.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten. It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H332,H373
• Indicaciones de precaución: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Órganos diana: Respiratory Tract
• Clase de almacenamiento: 13 - Non Combustible Solids
• ¿Qué está pasando?: WGK 2
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)