E6635

Ácido etilenodiaminotetraacético disodium salt dihydrate

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

• Sinónimos: EDTA disodium salt, EDTA-Na₂, Edatamil, Edetato disodium salt dihydrate, Etilenodiaminotetraacetato de disodio dihydrate, Sequestrene Na₂
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Número de CAS: 6381-92-6
• Peso molecular: 372.24
• Beilstein: 3900609
• Número CE: 205-358-3
• Código UNSPSC: 12352107
• ID de la sustancia en PubChem: 24894632
• NACRES: NA.77

Propiedades

• grado: Sigma Grade
• Ensayo: 98.5-101.5%
• Formulario: powder
• idoneidad de la reacción: reagent type: chelator
• técnicas: cell culture | plant: suitable
• mp: 248 °C (dec.) (lit.)
• solubilidad: H₂O: soluble, clear, colorless
• cadena SMILES: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• Clave InChI: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Descripción

Descripción general

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex.[1] Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.[2] It enhances the antibacterial activity of lysozyme.[3] EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.[4] EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis. [5]

Aplicación

Quelante de cationes divalentes. Inhibe las enzimas, como las metaloproteasas, que requieren cationes divalentes para ser activas.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species[6] and in protein extraction from Moss, Physcomitrella paten.[7] It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.[8]

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H332,H373
• Consejos de prudencia: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Órganos de actuación: Respiratory Tract
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)