The solution stability of this product has not been determined. However, an identical product, 219557, notes that solutions prepared in organic solvents, such as acetone, may be stored protected from light at -20°C for up to 3 months. It is recommended that aqueous solutions not be stored for more than 1 day.
C2389
Cerulenin
from Cephalosporium caerulens, ≥98% (HPLC), powder, de novo phospholipid synthesis inhibitor
Sinónimos:
Helicocerin, (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
5 mg | Comprobar disponibilidad del carrito | US$ 217,00 |
10 mg | Comprobar disponibilidad del carrito | US$ 434,00 |
50 mg | Comprobar disponibilidad del carrito | US$ 1.510,00 |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C12H17NO3
Número CAS:
Peso molecular:
223.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
241-424-8
MDL number:
Beilstein/REAXYS Number:
4140423
Assay:
≥98% (HPLC)
Form:
powder
US$ 217,00
PRECIOS SIN IMPUESTOS NACIONALES
Comprobar disponibilidad del carrito
Servicio técnico
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Permítanos ayudarleNombre del producto
Cerulenin, ≥98% (HPLC), from Cephalosporium caerulens
biological source
Cephalosporium caerulens
Quality Segment
assay
≥98% (HPLC)
form
powder
mp
93 °C
solubility
acetone: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to yellow
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
C/C=C/C/C=C/CCC([C@@H]1[C@H](C(N)=O)O1)=O
InChI
1S/C13H18O3/c1-3-4-5-6-7-8-9-11(15)13-12(16-13)10(2)14/h3-4,6-7,12-13H,5,8-9H2,1-2H3/b4-3+,7-6+/t12-,13+/m0/s1
InChI key
PTNNGEBMCNMENY-JIVMHGEESA-N
Gene Information
human ... FASN(2194)
General description
Cerulenin, an inhibitor of de novo phospholipid synthesis triggers apoptosis in various wild type p53 and mutant p53 tumor cell lines. This fungal antibiotic also blocks the condensing enzyme involved in fatty acid and polyketide biosynthesis.
Application
Cerulenin has been used:
- as a fatty acid synthase inhibitor to study its effects on aldosterone-induced trained immunity
- as a blocker of fatty acid synthase to study its effects on the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)
- as a supplement in yeast extract–peptone–dextrose/glycerol (YPD/G) agar plates for the isolation of cerulenin-resistant yeast strains
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Este artículo | |||
|---|---|---|---|
| description ≥98% (HPLC), from Cephalosporium caerulens | description ≥95% (HPLC) | description Pharmaceutical Secondary Standard; Certified Reference Material | description - |
| form powder | form powder | form - | form liquid |
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay - | assay - |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility acetone: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to yellow | solubility - | solubility - | solubility - |
| biological source Cephalosporium caerulens | biological source - | biological source - | biological source rabbit |
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Warning
Códigos de peligro
Hazard Classifications
Acute Tox. 4 Oral
Clase de almacenamiento
11 - Combustible Solids
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
dust mask type N95 (US), Eyeshields, Gloves
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HOW LONG IS CERULENIN STABLE FOR WHEN DISSOLVED IN ACETONE?
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