B3313

Bicyclol

≥98% (HPLC)

• Sinónimos: 4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl
• Fórmula empírica (notación de Hill): C₁₉H₁₈O₉
• Número de CAS: 118159-48-1
• Peso molecular: 390.34
• MDL number: MFCD00889471
• UNSPSC Code: 12352202
• PubChem Substance ID: 329773215
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: COC(=O)c1cc(OC)c2OCOc2c1-c3c(CO)cc(OC)c4OCOc34
• InChI: 1S/C19H18O9/c1-22-11-4-9(6-20)13(17-15(11)25-7-27-17)14-10(19(21)24-3)5-12(23-2)16-18(14)28-8-26-16/h4-5,20H,6-8H2,1-3H3
• InChI key: KXMTXZACPVCDMH-UHFFFAOYSA-N

Descripción

General description

Bicyclol has anti-inflammatory properties and enhances the prognosis of kidney transplantation. It is involved in the removal of reactive oxygen species and modulates cytokine secretion.

Biochem/physiol Actions

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C.

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.

Información de seguridad

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves