B0936

BRL 50481

≥98% (HPLC), solid

• Sinónimos: 5-Nitro-2,N,N-trimethylbenzenesulfonamide
• Fórmula empírica (notación de Hill): C₉H₁₂N₂O₄S
• Número CAS: 433695-36-4
• Peso molecular: 244.27
• NACRES: NA.77
• PubChem Substance ID: 24277757
• UNSPSC Code: 12352200
• MDL number: MFCD03039912
• Assay: ≥98% (HPLC)
• Form: solid

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white to off-white
• solubility: DMSO: >10 mg/mL, H₂O: insoluble
• originator: GlaxoSmithKline
• storage temp.: 2-8°C
• SMILES string: CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
• InChI: 1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3
• InChI key: IFIUFCJFLGCQPH-UHFFFAOYSA-N
• Gene Information: human ... PDE7A(5150), PDE7B(27115)

Descripción

Biochem/physiol Actions

BRL 50481 is a potent and selective PDE7 inhibitor (IC50 = 260 nM).

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)