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Merck
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Key Documents

AV39769

Sigma-Aldrich

Anti-CREB3L1 (AB2) antibody produced in rabbit

IgG fraction of antiserum

Sinónimos:

Anti-cAMP responsive element binding protein 3-like 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

57 kDa

species reactivity

rabbit, mouse, bovine, rat, guinea pig, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_443086

UniProt accession no.

Q96BA8

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CREB3L1(90993)

General description

CREB3L1 (OASIS) is a transcription factor that is involved in the regulation of endoplasmic reticulum (ER) stress. It activates extracellular matrix gene expression and may play a role in the development of pancreas. CREB3L1 modulates the expression of the vasopressin gene in the hypothalamus of rats. EWSR1-CREB3L1 fusion transcript has been implicated in small cell osteosarcoma.
Rabbit Anti-CREB3L1 antibody recognizes bovine, human, mouse, rat, and canine CREB3L1.

Immunogen

Synthetic peptide directed towards the N terminal region of human CREB3L1

Application

Rabbit Anti-CREB3L1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

Biochem/physiol Actions

The CREB3L1 gene encodes a protein with a transmembrane domain that is a transcriptional activator of the CREB/ATF family.

Sequence

Synthetic peptide located within the following region: MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDF

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Larisa V Debelenko et al.
Genes, chromosomes & cancer, 50(12), 1054-1062 (2011-10-12)
Cellular morphology of small cell osteosarcoma, an aggressive variant of osteosarcoma, is similar to Ewing sarcoma, but its molecular pathogenesis is largely unknown. We report the case of a 12-year-old girl with multifocal small cell osteosarcoma positive for the Ewing
Ravi N Vellanki et al.
Endocrinology, 151(9), 4146-4157 (2010-07-30)
Old astrocyte specifically induced substance (OASIS) has previously been shown to be a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation that is similar to ATF6. In this study we investigated the expression and activation
Yan Fan et al.
The Journal of biological chemistry, 291(43), 22819-22829 (2016-09-10)
HIV-1 Tat is a major culprit for HIV/neuroAIDS. One of the consistent hallmarks of HIV/neuroAIDS is reactive astrocytes or astrocytosis, characterized by increased cytoplasmic accumulation of the intermediate filament glial fibrillary acidic protein (GFAP). We have shown that that Tat
Mingkwan Greenwood et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(11), 3810-3820 (2014-03-14)
Arginine vasopressin (AVP) is a neurohypophysial hormone regulating hydromineral homeostasis. Here we show that the mRNA encoding cAMP responsive element-binding protein-3 like-1 (CREB3L1), a transcription factor of the CREB/activating transcription factor (ATF) family, increases in expression in parallel with AVP

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