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Merck

86500

Sigma-Aldrich

Testosterone

purum, ≥99.0% (HPLC)

Sinónimos:

17β-Hydroxy-3-oxo-4-androstene, 17β-Hydroxy-4-androsten-3-one, 4-Androsten-17β-ol-3-one, trans-Testosterone

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About This Item

Fórmula empírica (notación de Hill):
C19H28O2
Número de CAS:
Peso molecular:
288.42
Beilstein:
1915399
Número CE:
Número MDL:
Código UNSPSC:
51111800
ID de la sustancia en PubChem:
NACRES:
NA.77
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

purum

Nivel de calidad

Ensayo

≥99.0% (HPLC)

Formulario

powder

actividad óptica

[α]20/D +110±2°, c = 1% in ethanol

control farmacológico

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

152-156 °C

cadena SMILES

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

Clave InChI

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Información sobre el gen

human ... AR(367)

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Acciones bioquímicas o fisiológicas

Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.

Cláusula de descargo de responsabilidad

Sales restrictions may apply.

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Frances S Chen et al.
Social cognitive and affective neuroscience, 10(6), 797-800 (2014-09-07)
Physical size and strength are associated with dominance and threat. The current study tested (i) whether men's evaluations of male strangers would be negatively influenced by cues indicating physical formidability, and (ii) whether these evaluations would be influenced by oxytocin
Andrea C Lo et al.
International journal of radiation oncology, biology, physics, 88(1), 87-93 (2013-12-18)
To determine (1) the prognostic utility of prostate-specific antigen (PSA) concentration at 45 to 60 months (48mPSA) after low-dose-rate prostate brachytherapy (LDR-PB); (2) the predictors of 48mPSA; and (3) the prognostic utility of directional trends between PSA levels at 24
James R Bell et al.
American journal of physiology. Heart and circulatory physiology, 306(9), H1265-H1274 (2014-03-13)
Estrogen in females is conventionally considered a cardioprotective influence, but a role for estrogen in male cardioprotection has yet to be defined. Estrogen biosynthesis from testosterone is regulated by aromatase. Aromatase has recently been shown to be expressed in the
E David Crawford et al.
Urology, 83(5), 1122-1128 (2014-03-26)
To demonstrate the safety and efficacy of up to 5 years of degarelix treatment and the effects of crossing over from leuprolide to degarelix in the extension phase of a phase III pivotal 1-year trial. Patients receiving degarelix who completed
Franck Oury et al.
The Journal of clinical investigation, 123(6), 2421-2433 (2013-06-04)
The osteoblast-derived hormone osteocalcin promotes testosterone biosynthesis in the mouse testis by binding to GPRC6A in Leydig cells. Interestingly, Osteocalcin-deficient mice exhibit increased levels of luteinizing hormone (LH), a pituitary hormone that regulates sex steroid synthesis in the testes. These

Questions

1–3 of 3 Questions  
  1. How should I dissolve product #86500 Testosteron in 100% ethanol? Is it soluble? Should I store it in ethanol or dilute it in medium? Please provide more information.

    1 answer
    1. This product is soluble in chloroform at 100 mg/mL, in methanol and absolute ethanol at 0.5 mg/mL, and in a 45%(w/v) aqueous 2-hydroxypropyl-b-cyclodextrin solution at 18.2 mg/mL. This material is also soluble in vegetable oils and dioxane and slightly soluble in methyl oleate. The stock solution may be diluted with aqueous buffer or medium to the required working concentration. The stability of working solutions of this material has not been determined.

      Helpful?

  2. What is the recommended reconstitution of this product?

    1 answer
    1. This product is soluble in chloroform at 100 mg/mL, in methanol and absolute ethanol at 0.5 mg/mL, and in a 45%(w/v) aqueous 2-hydroxypropyl-b-cyclodextrin solution at 18.2 mg/mL. This material is also soluble in vegetable oils and dioxane and slightly soluble in methyl oleate.

      Helpful?

  3. Muy buenos días, a qué temperatura debe mantenerse este producto (testosterone 86500) para su almacenamiento a medio y largo plazo?

    1 answer
    1. This product may be stored at room temperature in powder form. Solutions are stable and refrigerated for up to 30 days. For long-term solution storage, aliquot and store at -20°C. This product is not assigned an expiration date or recommended retest date. Customers should routinely inspect products with no expiration date or recommended retest date to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

      Please see the link below to review the product datasheet for the Sigma-Aldrich brand Testosterone, T1500:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/332/257/t1500dat.pdf

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