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75633

Osmium tetroxide solution

Name: Osmium tetroxide solution
Brand: SIGMA
Price: 579 USD

suitable for electron microscopy, 2% in H₂O

Sinónimos:

Osmium(IV) oxide

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Talla/SKU	Disponibilidad	Precio
2 mL	Comprobar disponibilidad del carrito	US$ 579,00

Acerca de este artículo

Fórmula lineal:

OsO₄

Número CAS:

20816-12-0

Peso molecular:

254.23

NACRES:

NA.47

PubChem Substance ID:

57652577

UNSPSC Code:

12171500

MDL number:

MFCD00011150

Form:

solution

US$ 579,00

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Propiedades

form

solution

Quality Segment

100

reaction suitability

reagent type: oxidant

concentration

2% in H₂O

technique(s)

electron microscopy: suitable

color

colorless to yellow

density

1.0 g/mL at 20 °C

application(s)

hematology
histology

storage temp.

2-8°C

SMILES string

O=[Os](=O)(=O)=O

InChI

1S/4O.Os

InChI key

VUVGYHUDAICLFK-UHFFFAOYSA-N

Descripción

General description

Osmium tetroxide (OsO4) also referred to as osmium, is a heavy tetrahedral, symmetrical molecule. It is both a dye and a non-coagulant fixative agent in electron microscopy primarily used for the examination of biological tissue components in the histopathology laboratory. Specimens are postfixed with osmium tetroxide to ensure the preservation of the lipids.

Application

Osmium tetroxide solution has been used as a fixative in electron microscopy.

Biochem/physiol Actions

Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.

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Este artículo	251755	208868	75632
Sigma-Aldrich 75633 Osmium tetroxide solution	Sigma-Aldrich 251755 Osmium tetroxide solution	Sigma-Aldrich 208868 Osmium tetroxide solution	Sigma-Aldrich 75632 Osmium tetroxide solution
description suitable for electron microscopy, 2% in H₂O	description 4 wt. % in H₂O	description 2.5 wt. % in tert-butanol	description suitable for electron microscopy, 4% in H₂O
form solution	form liquid	form liquid	form solution
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
density 1.0 g/mL at 20 °C	density 1.04 g/mL at 25 °C, 1.0 g/mL at 20 °C	density 0.811 g/mL at 25 °C, 1.0 g/mL at 20 °C	density 1.0 g/mL at 20 °C
reaction suitability reagent type: oxidant	reaction suitability reagent type: oxidant	reaction suitability reagent type: oxidant	reaction suitability reagent type: oxidant
technique(s) electron microscopy: suitable	technique(s) -	technique(s) -	technique(s) electron microscopy: suitable
concentration 2% in H₂O	concentration 4 wt. % in H₂O, 3.5-4.5% (OsO₄)	concentration 2.5 wt. % in tert-butanol	concentration 4% in H₂O

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Pictogramas

GHS06,GHS05

Palabra de advertencia

Danger

Códigos de peligro

H302 + H332,H310,H315,H318

Indicaciones de precaución

P262 - P280 - P301 + P312 - P302 + P352 + P310 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Clase de almacenamiento

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

¿Qué está pasando?

WGK 1

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Lot/Batch Number

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