61743

N-Lauroilsarcosina sodium salt

BioUltra, ≥99.0% (HPLC)

• Sinónimos: N-Dodecanoil-N-metilglicina sodium salt, Sarkosyl NL
• Fórmula lineal: CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Número de CAS: 137-16-6
• Peso molecular: 293.38
• Beilstein: 5322974
• Número CE: 205-281-5
• Número MDL: MFCD00042728
• Código UNSPSC: 12161900
• ID de la sustancia en PubChem: 57651862
• NACRES: NA.25

Propiedades

• grado: Molecular Biology
• Nivel de calidad: 200
• descripción: anionic
• Línea del producto: BioUltra
• Ensayo: ≥99.0% (HPLC)
• Formulario: powder
• mol peso: micellar avg mol wt 600; average mol wt 600
• número de agregación: 2
• impurezas: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• pérdida: ≤1% loss on drying, 110 °C
• pH: 7.0-9.0 (25 °C, 1 M in H₂O)
• CMC: 14.6 mM (20-25°C)
• solubilidad: H₂O: 1 M at 20 °C, clear, colorless
• trazas de anión: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• trazas de catión: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorción UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.06
• cadena SMILES: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• aplicaciones: sample preservation
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• Clave InChI: KSAVQLQVUXSOCR-UHFFFAOYSA-M

Descripción

Descripción general

The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).[1]

Aplicación

N-Lauroylsarcosine sodium salt has been used as a component:

• of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
• of proteinase K solution for the heat denaturation of genomic DNA
• of 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer
• in the hybridization buffer for in situ hybridization histochemistry[2]
• in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin[3]
• in proteinase K solution to inactivate the enzymes[4]

Otras notas

Tensioactivo aniónico.

Información de seguridad

• Pictogramas: GHS06,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H315,H318,H330
• Consejos de prudencia: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 512.6 °F - closed cup
• Punto de inflamabilidad (°C): 267 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)