53727
N-(3-Hydroxydodecanoyl)-DL-homoserine lactone
≥97% (HPLC)
Sinónimos:
3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)dodecanamide
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10 MG
US$ 326,00
US$ 326,00
PRICE WITHOUT NATIONAL TAXES
Fecha estimada de envío31 de mayo de 2025
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10 MG
US$ 326,00
About This Item
Fórmula empírica (notación de Hill):
C16H29NO4
Número de CAS:
Peso molecular:
299.41
Número MDL:
Código UNSPSC:
41116134
ID de la sustancia en PubChem:
NACRES:
NA.25
US$ 326,00
PRICE WITHOUT NATIONAL TAXES
Fecha estimada de envío31 de mayo de 2025
Solicitar un pedido a granel
Productos recomendados
Ensayo
≥97% (HPLC)
composición
carbon, 63.5-64.9%
nitrogen, 4.4-4.9%
temp. de almacenamiento
−20°C
cadena SMILES
CCCCCCCCCC(O)CC(=O)NC1CCOC1=O
InChI
1S/C16H29NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h13-14,18H,2-12H2,1H3,(H,17,19)
Clave InChI
RGTXFFYJJNWEPV-UHFFFAOYSA-N
Acciones bioquímicas o fisiológicas
N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see[1][2][3][4][5]. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs[3], and a research focus for the prevention of biofilm formation[6][7][8].
Quorum-sensing signal generation
Envase
Bottomless glass bottle. Contents are inside inserted fused cone.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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B M Davis et al.
Biophysical journal, 101(1), 245-254 (2011-07-05)
A practical label-free method for the rapid determination of small-molecule critical micelle concentration (CMC) using a fixed-angle light-scattering technique is described. Change in 90° light scattering at a fixed wavelength of incident radiation with increasing bacterial quorum molecule concentration and
L Passador et al.
Journal of bacteriology, 178(20), 5995-6000 (1996-10-01)
A series of structural analogs of the Pseudomonas aeruginosa autoinducer [PAI, N-3-oxo-dodecanoyl homoserine lactone] were obtained and tested for their ability to act as autoinducers in stimulating the expression of the gene for elastase (lasB) by measuring beta-galactosidase production from
Tommaso R I Cataldi et al.
Journal of mass spectrometry : JMS, 43(1), 82-96 (2007-08-22)
A method for the comprehensive profiling of the N-acyl-homoserine lactone (AHL) family of bacterial quorum-sensing molecules is presented using liquid chromatography (LC) coupled to a hybrid quadrupole linear ion trap (LTQ) and Fourier-transform ion-cyclotron-resonance mass spectrometer (FTICR). We demonstrate an
Meng Gui et al.
Frontiers in microbiology, 9, 1712-1712 (2018-08-16)
Sturgeon is an important fresh water-culture fish in China. A problem with sturgeon is its high susceptibility to spoilage. Food spoilage is reported to be regulated by quorum sensing (QS). To identify the QS signals acetylated homoserine lactones (AHLs) in
Kaoru Yamabe et al.
Biomedical research (Tokyo, Japan), 41(6), 259-268 (2020-12-04)
Recently, opportunistic nosocomial infections caused by Acinetobacter baumannii have become increasingly prevalent worldwide. The pathogen often establishes biofilms that adhere to medical devices, causing chronic infections refractory to antimicrobial therapy. Clinical reports have indicated that some macrolide antibiotics are effective
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