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Documentos clave

R0950000

Rifamycin S

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

1,4-Dideoxy-1,4-dihydro-1,4-dioxorifamycin

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About This Item

Fórmula empírica (notación de Hill):
C37H45NO12
Número de CAS:
13553-79-2
Peso molecular:
695.75
Código UNSPSC:
41116107
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

pharmaceutical primary standard

familia API

rifamycin, rifampicin

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

N1C2=CC(=O)c3c4c(c(c(c3C2=O)O)C)O[C@](O\C=C\[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]([C@H](\C=C\C=C(/C1=O)\C)C)O)C)O)C)OC(=O)C)C)OC)(C4=O)C

InChI

1S/C37H45NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,41-43H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1

Clave InChI

BTVYFIMKUHNOBZ-ODRIEIDWSA-N

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Rifamycin S EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

R1000000

Rifamycin sodium, European Pharmacopoeia (EP) Reference Standard

R0700000

Rifampicina, European Pharmacopoeia (EP) Reference Standard

R0800000

Rifampicin quinone, European Pharmacopoeia (EP) Reference Standard

R0900000

Rifamycin B, European Pharmacopoeia (EP) Reference Standard

1604202

Rifampicin quinone, United States Pharmacopeia (USP) Reference Standard

PHR1664

Rifamycin Sodium, Pharmaceutical Secondary Standard; Certified Reference Material

BP400

Rifampicine N-oxide, British Pharmacopoeia (BP) Reference Standard

BP627

3-Formylrifamycin SV, British Pharmacopoeia (BP) Reference Standard

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palabra de señalización

Warning

Frases de peligro

H371,H410

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 2

Órganos de actuación

Liver

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Micah Steffek et al.
Biochemistry, 42(41), 12067-12076 (2003-10-15)
Mycothiol is comprised of N-acetylcysteine (AcCys) amide linked to 1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside (GlcN-Ins) and is the predominant thiol found in most actinomycetes. Mycothiol S-conjugate amidase (Mca) cleaves the amide bond of mycothiol S-conjugates of a variety of alkylating agents and xenobiotics
Molecular structure and conformation of rifamycin S, a potent inhibitor of DNA-dependent RNA polymerase.
S K Arora et al.
The Journal of antibiotics, 45(3), 428-431 (1992-03-01)
Ming Chen et al.
The Journal of organic chemistry, 78(1), 3-8 (2012-06-19)
Syntheses of the C(15)-C(27) fragments of chaxamycins A/D, rifamycin S, and the C(12)-C(24) fragment of salinisporamycin have been accomplished in 10 steps from commercially available starting materials. Three crotylboron reagents were utilized to construct the seven contiguous stereocenters in these
U C Banerjee
Enzyme and microbial technology, 15(12), 1037-1041 (1993-12-01)
Growing and resting cell systems of Curvularia lunata were used for the transformation of rifamycin B to rifamycin S. In the case of growing cells, rifamycin B was added at the time of inoculation and at the different phases of
K W Hunt et al.
Organic letters, 3(3), 481-484 (2001-06-29)
[figure: see text] The direct opening at the bridgehead of oxabicyclo[3.2.1]octenes employing silyl ketene acetals in 4.0-5.0 M lithium perchlorate in diethyl ether has been realized, which gives rise to highly functionalized cycloheptadienes that can be further manipulated for use
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