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Merck
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D0513

Supelco

Dibucaine

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C20H29N3O2
Número de CAS:
85-79-0
Peso molecular:
343.46
EC Number:
201-632-1
MDL number:
MFCD00047595
UNSPSC Code:
41116107
PubChem Substance ID:
24893238

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Potent, long-acting local anesthetic

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number

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Jamie Nelsen et al.
Pediatric emergency care, 25(10), 670-673 (2009-10-17)
Dibucaine is considered one of the most potent and consequently toxic amide anesthetics available, and despite withdrawal from the US market as a spinal anesthetic, it remains accessible as an over-the-counter preparation in the United States. Dibucaine exposures in children
A Seelig
Cell biology international reports, 14(4), 369-380 (1990-04-01)
The interaction between lipids and water soluble amphiphiles was investigated by means of a monolayer technique, monitoring the area increase at constant surface pressure. The area increase could be quantitated and binding isotherms at different surface pressures were measured. A
M Laura Parnas et al.
American journal of clinical pathology, 135(2), 271-276 (2011-01-14)
Butyrylcholinesterase (BChE) metabolizes the paralytic succinylcholine. Extended paralysis occurs in people with inherited BChE variants that may be identified by measuring BChE activity with and without the inhibitor dibucaine to calculate a dibucaine number (DN). Accurate phenotyping requires phenotype-specific BChE
Thaïs Souto-Padrón et al.
Parasitology research, 99(4), 317-320 (2006-04-14)
Although local anesthetics (LA) are considered primarily Na+-channel blockers in the past decade, an alternative action of LA as inhibitors of fusion among compartments of the endocytic/exocytic pathways was described. In epimastigote forms of Trypanosoma cruzi, we observed that 50
Jared A Baird et al.
Pharmaceutical research, 29(1), 271-284 (2011-07-26)
Understanding the critical factors governing the crystallization tendency of organic compounds is vital when assessing the feasibility of an amorphous formulation to improve oral bioavailability. The objective of this study was to investigate potential links between viscosity and crystallization tendency
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