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Merck

68909

Supelco

Sennoside A

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C42H38O20
Número de CAS:
Peso molecular:
862.74
Beilstein/REAXYS Number:
5723746
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥96.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(cc(O)c8C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1

InChI key

IPQVTOJGNYVQEO-GTCVFCFLSA-N

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General description

Sennoside A is a hydroxy anthracene glycoside generally present in the polyherbal formulations that contain Cassia angustifolia leaves, which is used in the treatment of constipation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Los clientes también vieron

Slide 1 of 5

1 of 5

Status of sennosides content in various Indian herbal formulations: method standardization by HPTLC
Aktar W, et al.
Bangladesh Journal of Pharmacology, 3, 64-68 (2008)
Jing Xiao et al.
Wei sheng yan jiu = Journal of hygiene research, 40(3), 355-357 (2011-06-24)
To develop an analytical method for determination of sennoside A and sennoside B simultaneously in health food by high performance liquid chromatography (HPLC). Samples were extracted by ultrasound extraction and determined by HPLC with a UV detector. Using a Synergi
Emi Matsui et al.
Biological & pharmaceutical bulletin, 34(9), 1438-1442 (2011-09-02)
Daiokanzoto (DKT), a Kampo medicine that includes the combination of two crude drugs (rhubarb and glycyrrhiza), is clinically effective for constipation. The aim of this study is to clarify the influence of glycyrrhiza, three glycyrrhiza constituents (glycyrrhizin, liquiritin, and liquiritin
Mitsuko Takahashi et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 50(6), 297-303 (2010-01-13)
Sennoside A and B were detected in 21 commercial health tea products surveyed in 2000-2007, but there were 8 products in which the leaves could not be identified as senna because the leaves had become discolored. The results of assay
Huifang Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(3), 302-304 (2012-05-10)
To determine the difference on purgative biopotency of different processed products of rhubarb and compare rhubarb before and after preparation. The prime biopotency of rhubarb reference substance was determined by comparing with the control substance of sennoside B using rat

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