394874

1-(Trimethylsilyl)imidazole

for GC derivatization, LiChropur^™

• Sinónimos: TSIM, N-Trimethylsilylimidazole, TMSI
• Fórmula empírica (notación de Hill): C₆H₁₂N₂Si
• Número de CAS: 18156-74-6
• Peso molecular: 140.26
• Beilstein: 606148
• Número CE: 242-040-3
• Número MDL: MFCD00005280
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 329755874
• NACRES: NA.22

Propiedades

• grado: for GC derivatization
• Nivel de calidad: 100
• Ensayo: ≥94.0%
• calidad: LiChropur^™
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Silylations
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.475 (lit.)
• bp: 93-94 °C/14 mmHg (lit.)
• densidad: 0.956 g/mL at 25 °C (lit.)
• cadena SMILES: C[Si](C)(C)n1ccnc1
• InChI: 1S/C6H12N2Si/c1-9(2,3)8-5-4-7-6-8/h4-6H,1-3H3
• Clave InChI: YKFRUJSEPGHZFJ-UHFFFAOYSA-N

Descripción

Descripción general

1-(Trimethylsilyl)imidazole (TMSIM) has high silyl donor ability. It does not react with amino groups and also does not help in formation of enol-ether on unprotected ketone groups. It is useful as a silylating agent for ecdysones, norepinephrine, dopamine, steroids, sugars, sugar phosphates and ketose isomers.[1]

Powerful silylating agent, particularly for alcohols[2][3][4]; Synthesis of acyl imidazolides[5]

Aplicación

1-(Trimethylsilyl) imidazole may be used for the synthesis an O-silylated derivative of a hexahomotriazacalix[3]arene.[6] It may also be used for the silylation of Ti-MCM-41 catalyst, to study its effect on the olefin epoxidation with aqueous H₂O₂, 1-(Trimethylsilyl) imidazole was found to improve the hydrophobicity and the catalytic performance of Ti-MCM-41.[7]

Learn more in the Product Information

Otras notas

Reagent for trimethylsilyl and trimethylsilyl ether.

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H302,H315,H319
• Consejos de prudencia: P210 - P233 - P240 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 42.8 °F - closed cup
• Punto de inflamabilidad (°C): 6 °C - closed cup
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter