CB1015

Anti-GTAP Rabbit pAb

liquid, Calbiochem^®

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• contains: ≤0.1% sodium azide as preservative
• species reactivity: mouse, rat, human
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: ambient
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... UBE2Q1(55585)

Descripción

General description

Anti-GTAP, rabbit polyclonal, recognizes the ~67 kDa GTAP protein in HEK293 cells. It is validated for use in Western blotting.

Protein A purified rabbit polyclonal antibody. Recognizes the ~67 kDa GTAP protein.

Recognizes the ~67 kDa GTAP protein in HEK293 cells.

Hu Entrez ID: 55585

Mu Entrez ID: 70093

Rat Entrez ID: 295292

Target NCBI Accession: HP 060052.3

Target SwissProt: Q7Z7E8

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). GTAP is a member of the E2 ubiquitin-conjugating enzyme family. GTAP may participate in intercellular adhesion and embryonic development. GTAP is thought to play a role in stem cell development via its regulation of laminin-dependent embryonic cell adhesion and the formation of embryoid bodies.

Immunogen

A synthetic peptide corresponding to amino acids 7-22 (QGQQQPGPGQQLGGQG) of human GTAP, conjugated to KLH.

Human

Application

Immunoblotting (3-10 g/ml)

Warning

Toxicity: Regulatory Review (Z)

Physical form

In PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Due to a high degree of sequence identity, this antibody is also expected to react with mouse and rat GTAP. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable