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AB9014

Sigma-Aldrich

Anti-Chx10 Antibody, CT

Chemicon®, from sheep

Sinónimos:

Hox-10, Ocular Retardation, C. Elegans ceh-10 Homeo Domain Containing Homolog

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

sheep

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, bovine, human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_182894.2

UniProt accession no.

P58304

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... VSX2(338917)

Specificity

Chx10

Immunogen

Epitope: C-terminus
Recombinant human Chx10 protein, C-terminal.

Application

Immunoblotting: 0.5-1.0 μg/mL. Reacts with the 46 kD protein in rat and mouse retinal tissue lysate.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers
This Anti-Chx10 Antibody, C-terminus is validated for use in WB for the detection of Chx10.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Rowena Smith et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(33), 7975-7993 (2017-07-22)
During vertebrate eye morphogenesis, a transient fissure forms at its inferior part, known as the optic fissure. This will gradually close, giving rise to a healthy, spherical optic cup. Failure of the optic fissure to close gives rise to an
Proliferation and expression of progenitor and mature retinal phenotypes in the adult mammalian ciliary body after retinal ganglion cell injury.
Nickerson, PE; Emsley, JG; Myers, T; Clarke, DB
Investigative Ophthalmology & Visual Science null
Ke Zhang et al.
Investigative ophthalmology & visual science, 64(15), 32-32 (2023-12-22)
Retinal ganglion cells (RGCs) are the projection neurons of the retina. Loss of RGCs is the cellular basis for vision loss in patients with glaucoma. Finding ways to regenerate RGCs will aid in the development of regenerative therapies for patients
Yanling Xin et al.
eLife, 11 (2022-12-03)
N 6-methyladenosine (m6A) is the most prevalent mRNA internal modification and has been shown to regulate the development, physiology, and pathology of various tissues. However, the functions of the m6A epitranscriptome in the visual system remain unclear. In this study
Kiyo Sakagami et al.
Molecular and cellular neurosciences, 49(2), 171-183 (2011-12-14)
The lipid phosphatase PTEN is a critical negative regulator of extracellular signal-induced PI3K activities, yet the roles of PTEN in the neural retina remain poorly understood. Here, we investigate the function of PTEN during retinal development. Deletion of Pten at

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