662041

U-73343

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

• Sinónimos: U-73343, 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
• Fórmula empírica (notación de Hill): C₂₉H₄₂N₂O₃
• Número de CAS: 142878-12-4
• Peso molecular: 466.66
• Número MDL: MFCD00211221
• Código UNSPSC: 51111800
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• color: off-white
• solubilidad: ethanol: 1 mg/mL; DMSO: 2 mg/mL; chloroform: 200 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 10-30°C
• cadena SMILES: N5(C(=O)CCC5=O)CCCCCCN[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)OC)CC3)CC1)C
• InChI: 1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
• Clave InChI: CJHWFIUASFBCKN-ZRJUGLEFSA-N

Descripción

Descripción general

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
Negative control of U-73122 in the inhibition of phospholipase C

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Irritant (B)

Reconstitución

For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

Otras notas

Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther.255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther.253, 688.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable