459616

Okadaic Acid, Ammonium Salt

Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

• Sinónimos: Okadaic Acid, Ammonium Salt
• Fórmula empírica (notación de Hill): C₄₄H₆₇O₁₃ · NH₄
• Número de CAS: 155716-06-6
• Peso molecular: 822.03
• Número MDL: MFCD00153856
• Código UNSPSC: 12352106
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (TLC)
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: white
• solubilidad: water: 1 mg/mL; DMSO: 20 mg/mL; ethanol: 20 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: [N+H4].[O-]C(=O)[C@](O)(C[C@H]1O[C@]2(O[C@@H](CC(=C2)C)[C@H](C)\C=C\[C@@H]3O[C@@]4(O[C@H]5[C@@H](C(=C)[C@H](OC5CC4)[C@@H](O)C[C@@H](C6O[C@]7(OCCCC7)CC[C@H]6C)C)O)CC3)[C@@H](CC1)O)C
• InChI: 1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
• Clave InChI: ZBOMSHVRJSJGNR-JBNKPAQWSA-N

Descripción

Descripción general

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
PP1, PP2A

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Toxic (F)

Otras notas

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992. Blood80, 2911.
Normura, M., et al. 1992. Biochemistry31, 11915.
Song, Q., et al. 1992. J. Cell Physiol.153, 550.
Tada, T., et al. 1992. Immunopharmacol.24, 17.
Cohen, P., et al. 1990. Trends Biochem. Sci.15, 98.
Cohen, P., et al. 1989. Annu. Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989. Nature337, 78.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301 + H311 + H331,H315
• Consejos de prudencia: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3