407135-M

Caged Ins(1,4,5)P₃, Trisodium Salt

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase.

• Sinónimos: Caged Ins(1,4,5)P₃, Trisodium Salt, D- myo-Inositol 1,4,5-Trisphosphate, P ⁴⁽⁵⁾-1-(2-Nitrophenyl)ethyl Ester, 3Na
• Fórmula empírica (notación de Hill): C₁₄H₁₉NO₁₇P₃ · 3Na
• Peso molecular: 635.19
• Código UNSPSC: 12352211

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥90% (HPLC)
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated; protect from light
• color: off-white
• solubilidad: water: 1 mg/mL
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Extinction coefficient (265 nm, H₂O): 4240 M^-1cm^-1.

Note: 1 set = 10 x 10 µg.

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase (extinction coefficient: 4240 M^-1cm^-1; 265 nm, H₂O). A mixture of two isomers with a cage on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P₃.

Acciones bioquímicas o fisiológicas

Primary Target
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Otras notas

Walker, J.W., et al. 1987. Nature327, 249.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable