344038

cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem

• Sinónimos: cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem, 4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor III
• Fórmula empírica (notación de Hill): C₂₅H₂₃N₃O₃S
• Número de CAS: 959861-21-3
• Peso molecular: 445.53
• UNSPSC Code: 12352200

Propiedades

• assay: ≥97% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: yellow
• solubility: DMSO: 100 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C

Descripción

General description

This product has been discontinued.

A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC₅₀ = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC₅₀ = 0.1 and 10 µM, respectively).

A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC₅₀ = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC₅₀ = 0.1 and 10 µM, respectively).

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett.17, 6257.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 10-13 - German Storage Class 10 to 13