263275

Desmosine

A novel quaternary pyridinium poly-amino acid present in elastin.

• Sinónimos: Desmosine
• Fórmula empírica (notación de Hill): C₂₄H₃₉N₅O₈
• Peso molecular: 525.60
• UNSPSC Code: 12352200

Propiedades

• Quality Level: 100
• assay: ≥99% (TLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic); protect from light
• solubility: water: 10 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Descripción

General description

A novel quaternary pyridinium poly-amino acid present in elastin. Suggested to be responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity.

A novel quaternary pyridinium poly-amino acid present in elastin. Suggested to be responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. Absorption max: 268 nm.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Cross-linking of elastin

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Akagawa, M., and Suyama, K. 2000. Connect. Tissue Res.41, 131.
Bode, D.C., et al. 2000. Pulm. Pharmacol. Therap.13, 175.
Viglio, S., et al. 2000. Eur. Respir. J.15, 1039.
Davis, N.R., and Anwar, R.A. 1970. J. Am. Chem. Soc.92, 3778.
Thomas, J., et al. 1963. Nature200, 651.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable