06-236
Anti-Giα1/2 Antibody
Upstate®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat, bovine
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GNAI1(2770)
Specificity
Recognizes Giα1 and Giα2.
Immunogen
10 residue synthetic peptide (KNNLKDCGLF) corresponding to the c-terminus of Gia1 and Gia2
Application
Detect Giα1/2 using this Anti-Giα1/2 Antibody validated for use in IC, IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
GPCR, cAMP/cGMP & Calcium Signaling
Quality
routinely evaluated by immunoblot on Rat Brain Microsomal Preparation or solubilized plasma membranes from mouse 3T3/A31 fibroblasts
Target description
40 kDa
Physical form
A diluted rabbit serum in PBS (50 mM KHPO4, 140 mM NaCl). Frozen solution
Format: Purified
Storage and Stability
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Widely expressed
Widely expressed
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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J M Sands et al.
The Journal of clinical investigation, 99(6), 1399-1405 (1997-03-15)
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P Barrett et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1619-1628 (2000-08-06)
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Jian Shi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(2), 702-715 (2015-10-16)
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The Journal of clinical investigation, 83(6), 2050-2062 (1989-06-01)
Adenylate cyclase in liver plasma membranes from streptozotocin-diabetic (STZ) or BB/Wor spontaneously diabetic rats showed increased responsiveness to GTP, glucagon, fluoroaluminate, and cholera toxin. Basal or forskolin-stimulated activity was unchanged in STZ rats, but increased in BB/Wor rats. No change
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