Full-length human origin recognition complex 6 (ORC6). Clone 3A4.
Application
Anti-ORC6 Antibody, clone 3A4 is a high quality Rat Monoclonal Antibody for the detection of ORC6 & has been validated in ChIP & WB.
Quality
Routinely evaluated by immunoblot.
Target description
30kDa A non specific protein was also detected at Mr 120kDa
Physical form
Format: Purified
Analysis Note
Control Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Human molecular genetics, 19(1), 99-110 (2009-10-10)
Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA polymerase inhibitor, aphidicolin (APH), slows the replication rate throughout
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus.
Mapping origins of replication has been challenging in higher eukaryotes. We have developed a rapid, genome-wide method to map origins of replication in asynchronous human cells by combining the nascent strand abundance assay with a highly tiled microarray platform, and
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