Anti-Endostatin Antibody, clone 1837.46 is an antibody against Endostatin for use in WB, IH.
Research Category Cell Structure
Research Sub Category ECM Proteins
Calidad
routinely evaluated by immunoblot on 3T3 cell lysates
Descripción de destino
Recognizes endostatin, Mr 22kDa An unidentified protein is also weakly detected at Mr 54kDa
Forma física
50mM sodium phosphate, pH 8.0, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified
Thiophilic chromatography
Almacenamiento y estabilidad
2 years at -20°C
Información legal
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Certificados de análisis (COA)
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Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been examined in human brain tumors. The authors report the production of a monoclonal antibody and detection of endostatin in
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 42(12), 1150-1155 (2009-11-07)
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation
The Journal of biological chemistry, 274(17), 11721-11726 (1999-04-17)
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells
Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4802-4807 (2000-04-12)
Inhibition of angiogenesis has been shown to be an effective strategy in cancer therapy in mice. However, its widespread application has been hampered by difficulties in the large-scale production of the antiangiogenic proteins. This limitation may be resolved by in
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Gunsalus, KT; Wagoner, MP; Meyer, K; Potter, WB; Schoenike, B; Kim, S; Alexander et al.
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