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T-018

Supelco

(−)-11-nor-9-Carboxy-Δ9-THC solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C21H28O4
Número de CAS:
56354-06-4
Peso molecular:
344.44
EC Number:
200-659-6
MDL number:
MFCD02682121
UNSPSC Code:
41116107
PubChem Substance ID:
329826589
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

suitability

suitable for immunoassay

application(s)

cannabis testing
forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

CCCCCC(C=C1O)=CC2=C1[C@@]3([H])[C@@](C(C)(C)O2)([H])CCC(C(O)=O)=C3

InChI

1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)/t15-,16-/m1/s1

InChI key

YOVRGSHRZRJTLZ-HZPDHXFCSA-N

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General description

An analytical reference standard suitable in cannabinoid testing, clinical toxicology, forensic analysis, or urine drug testing by LC-MS/MS or GC/MS. Also known as THC acid, 11-nor-9-Carboxy-Δ9-THC is the main secondary metabolite of THC found in urine or blood of cannabis users.

Application

  • Advanced analytical method development: A study by DeGregorio et al. introduces a Liquid Chromatography High-Resolution Mass Spectrometry (LC-HRMS) bioanalytical method for quantifying cannabinoids, including (−)-11-nor-9-Carboxy-Δ?-THC, in whole blood. This method is pivotal for determining recent cannabis use, offering significant advancements in forensic toxicology and drug testing (DeGregorio et al., 2020).
  • Cannabinoid serum analysis: Gottardo et al. present the first application of atmospheric-pressure chemical ionization gas chromatography tandem mass spectrometry for the determination of cannabinoids in serum. This groundbreaking technique enhances the detection and quantification of cannabinoids, including (−)-11-nor-9-Carboxy-Δ?-THC, facilitating deeper insights into cannabinoid pharmacokinetics and toxicology (Gottardo et al., 2019).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Referencia del producto
Descripción
Precios

T-003

(−)-Δ9-THC-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-004

(±)-11-nor-9-Carboxy-Δ9-THC-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-005

(−)-trans-Δ9-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-006

(±)-11-nor-9-Carboxy-Δ9-THC solution, 100 μg/mL in methanol, ampule of 1 mL, Cerilliant®

T-007

(±)-11-nor-9-Carboxy-Δ9-THC-D9 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-008

(±)-11-nor-9-Carboxy-Δ9-THC-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-011

(−)-Δ9-THC-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-019

(−)-11-nor-9-Carboxy-Δ9-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-038

(+)-11-Nor-Δ9-THC-9-carboxylic acid glucuronide solution, 100 μg/mL in methanol, ampule of 1 mL, Cerilliant®

T-080

(±)-cis-11-Nor-9-carboxy-Δ9-THC-D3 glucuronide solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cynthia Coulter et al.
Journal of analytical toxicology, 36(6), 413-417 (2012-04-26)
This paper describes the determination of tetrahydrocannabinol (THC) and its metabolite, 11-nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in oral fluid using solid-phase extraction and liquid chromatography with tandem mass spectral detection (LC-MS-MS) and its application to proficiency specimens. The method employs collection of
Yannick Lecompte et al.
Journal of analytical toxicology, 36(8), 569-574 (2012-08-31)
The guidelines for screening of urinary cannabinoids require that all specimens testing positive should be confirmed by gas chromatography-mass spectrometry at a confirmatory test cutoff value of 15 ng/mL of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH). To assess the impact of lowering the confirmatory
Vanessa de M Prata et al.
Analytical and bioanalytical chemistry, 403(2), 625-632 (2012-03-01)
A new procedure is described for the derivatization by silylation of 11-nor-Δ(9)-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) present in urine, followed by analysis using gas chromatography-tandem mass spectrometry. A conventional procedure for derivatization of the analyte was evaluated using two types of experimental
M Minoli et al.
Forensic science international, 218(1-3), 49-52 (2011-11-01)
The fine detection of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) in hair matrix remains one of the most important topics in hair analysis. This relevance lies in the necessity to obtain evidence of effective drug consumption and dispel any doubt of environmental contamination.
Andreas R Baudy et al.
The Journal of pharmacology and experimental therapeutics, 343(1), 225-232 (2012-06-30)
Glucocorticoids are standard of care for many inflammatory conditions, but chronic use is associated with a broad array of side effects. This has led to a search for dissociative glucocorticoids--drugs able to retain or improve efficacy associated with transrepression [nuclear
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