858125C

18:1 Lyso PG

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

• Sinónimos: 1-oleoy-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:1(9Z)/0:0); 110714
• Fórmula empírica (notación de Hill): C₂₄H₄₆O₉PNa
• Número de CAS: 326495-24-3
• Peso molecular: 532.58
• MDL number: MFCD00672604
• UNSPSC Code: 51191904
• NACRES: NA.25

Propiedades

• assay: >99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
• form: liquid
• packaging: pkg of 5 × 4 mL (858125C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 858125C
• concentration: 25 mg/mL (858125C-500mg)
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent.[1] Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.[2]

Application

18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.[3]

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol.[4] Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.[2]

Packaging

5 mL Clear Glass Sealed Ampule (858125C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable