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810131C

Avanti

16:0-12:0 NBD PC

Avanti Research™ - A Croda Brand 810131C

Sinónimos:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphocholine

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1 MG
US$ 274,00
5 MG
US$ 405,00

US$ 274,00

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1 MG
US$ 274,00
5 MG
US$ 405,00

About This Item

Fórmula empírica (notación de Hill):
C42H74N5O11P
Número de CAS:
105539-26-2
Peso molecular:
856.04
Número MDL:
MFCD00201281
Código UNSPSC:
12352211
NACRES:
NA.25

US$ 274,00

PRECIOS SIN IMPUESTOS NACIONALES
Check Cart for Availability
Solicitar un pedido a granel

Ensayo

>99% (TLC)

Formulario

liquid

envase

pkg of 1 × 1 mL (810131C-1mg)
pkg of 5 × 1 mL (810131C-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 810131C

concentración

1 mg/mL (810131C-1mg)
1 mg/mL (810131C-5mg)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Phosphatidylcholine (PC) is a common phospholipid found in eukaryotes and a prime metabolite of glycerolipid metabolism.[1] It is a vital component of the mucosal layer of the colon.[2] NBD PC is a fluorescently labeled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to phosphatidylcholine.[3]

Aplicación

16:0-12:0 NBD PC has been used as a fluorescent marker to study the adsorption of hyaluronan (HA) onto a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayer deposited on a silica surface by fluorescent microscopy.[4] It may also be used:
  • in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes[5]
  • as a fluorophore for DPPC in fluorescence recovery experiments[6]
  • as a substrate to test scramblase activity[7]

Acciones bioquímicas o fisiológicas

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is useful in the study of cellular processes as it functions as a fluorescent analog in lipid membranes and phospholipid phase transitions.[3]

Envase

5 mL Amber Glass Screw Cap Vial (810131C-1mg)
5 mL Amber Glass Screw Cap Vial (810131C-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Thomas Zander et al.
Colloids and surfaces. B, Biointerfaces, 142, 230-238 (2016-03-10)
The superior lubrication properties of synovial joints have inspired many studies aiming at uncovering the molecular mechanisms which give rise to low friction and wear. However, the mechanisms are not fully understood yet, and, in particular, it has not been
C Scomparin et al.
The European physical journal. E, Soft matter, 28(2), 211-220 (2008-12-23)
The diffusion law of DMPC and DPPC in Supported Lipid Bilayers (SLB), on different substrates, has been investigated in details by Fluorescence Recovery After Patterned Photobleaching (FRAPP). Over micrometer length scales, we demonstrate the validity of a purely Brownian diffusive
Yulia Y Tyurina et al.
The Journal of biological chemistry, 282(11), 8498-8509 (2007-01-19)
Macrophage recognition of apoptotic cells depends on externalization of phosphatidylserine (PS), which is normally maintained within the cytosolic leaflet of the plasma membrane by aminophospholipid translocase (APLT). APLT is sensitive to redox modifications of its -SH groups. Because activated macrophages
Ellen C Wrobel et al.
Physical chemistry chemical physics : PCCP, 22(11), 6154-6166 (2020-03-04)
The antibacterial activity of a calixarene derivative, p-tert-butylcalix[6]arene (Calix6), was assessed and was shown not to inhibit the growth of E. coli, S. aureus and B. subtilis bacteria. With the aim of gaining more insights into the absence of antibacterial
Rachel R Kroe et al.
Analytical biochemistry, 390(1), 1-13 (2008-12-24)
Analytical ultracentrifugation is a widely used method for characterizing the solution behavior of macromolecules. However, the two commonly used detectors, absorbance and interference, impose some fundamental restrictions on the concentrations and complexity of the solutions that can be analyzed. The
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