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790590P

Avanti

Bicelle Blend (DMPC:DHPC (2.8:1, mol:mol))

Avanti Research - A Croda Brand, powder

Sinónimos:

Bicelle Blend (DMPC:DHPC (2.8:1, mol:mol))

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

assay

99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (790590P-200MG)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

Bicelle blend contains 200mg of dimyristoylphosphatidylcholine (DMPC): dihexanoylphosphatidylcholine (DHPC) Pre-Mixed Bicelle (2.8:1, mol:mol). Bicelle is a discoidal lipid aggregate. It is made up of long-chain phospholipid and a detergent. The planar bilayer is generally composed of DMPC, which may have phospholipids with identical chain lengths but differ in the head group. The detergent layer is composed of a short-chain phospholipid like DHPC.[1]
The bicelle blend is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol: https://avantilipids.com/tech-support/liposome-preparation/bicelle-preparation/

Biochem/physiol Actions

Bicelles are used as membrane mimetics for studying membrane-associated biomolecules.[1]

Packaging

5ML Amber Glass Screw Cap Vial (790590P-200MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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K J Glover et al.
Biophysical journal, 81(4), 2163-2171 (2001-09-22)
Several complementary physical techniques have been used to characterize the aggregate structures formed in solutions containing dimyristoylphosphatidylcholine (DMPC)/dihexanoylphosphatidylcholine (DHPC) at ratios of < or =0.5 and to establish their morphology and lipid organization as that of bicelles. (31)P NMR studies

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