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790528P

Avanti

18:1 DGS-NTA

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (ammonium salt), powder

Sinónimos:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (ammonium salt); DOGS NTA

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5 MG
US$ 216,00

US$ 216,00

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5 MG
US$ 216,00

About This Item

Fórmula empírica (notación de Hill):
C53H100N5O13
Número de CAS:
474942-78-4
Peso molecular:
1015.39
Número MDL:
MFCD00057815
Código UNSPSC:
12352211
NACRES:
NA.25

US$ 216,00

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Check Cart for Availability
Solicitar un pedido a granel

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 5 mg (790528P-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 790528P

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA) is amphiphile.[1] DGS-NTA is a nitrilotriacetic acid -functionalized amphiphile devoid of nickel ion.[1]

Aplicación

18:1 DGS-NTA 1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (ammonium salt) has been used:
  • for generation of amphiphile monolayer [1]
  • in NTA-liposome preparation for procoagulant binding studies and to study its effect on factor FXII autoactivation[2]
  • as a liposome component for lipid bilayer preparation for surface plasmon resonance studies[3]

Acciones bioquímicas o fisiológicas

1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA or DOGS-NTA) cannot bind to histidine due to lack of nickel ion. It is capable of self-assembly to form a stable monolayer.[1] DOGS-NTA ammonium salt is useful in bicelle preparation. [4]

Envase

5 mL Clear Glass Sealed Ampule (790528P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

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Ronald D Seidel et al.
Journal of the American Chemical Society, 129(15), 4834-4839 (2007-03-28)
The study of bound-state conformations of ligands interacting with proteins is important to the understanding of protein function and the design of drugs that alter function. Traditionally, transferred nuclear Overhauser effects (trNOEs), measured from NMR spectra of ligands in rapid
N J Mutch et al.
Journal of thrombosis and haemostasis : JTH, 10(10), 2108-2115 (2012-08-22)
Upon contact with an appropriate surface, factor XII (FXII) undergoes autoactivation or cleavage by kallikrein. Zn(2+) is known to facilitate binding of FXII and the cofactor, high molecular weight kininogen (HK), to anionic surfaces. To investigate whether transition metal ions
Louis Gioia et al.
Science immunology, 4(38) (2019-09-01)
The class II region of the major histocompatibility complex (MHC) locus is the main contributor to the genetic susceptibility to type 1 diabetes (T1D). The loss of an aspartic acid at position 57 of diabetogenic HLA-DQβ chains supports this association;
Decorating liquid crystal surfaces with proteins for real-time detection of specific protein-protein binding
Hartono D, et al.
Advances in Functional Materials, 19(22), 3574-3579 (2009)
E Barklis et al.
The Journal of biological chemistry, 273(13), 7177-7180 (1998-04-29)
In an in vitro system that mimics the assembly of immature human immunodeficiency virus (HIV) particles, ordered arrays of HIV-1 capsid (CA) proteins encoded by the viral gag gene have been obtained by incubation of histidine-tagged capsid proteins (His-HIVCA) beneath
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