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850217

Sigma-Aldrich

3,4-Dihydroxyphenylacetic acid

98%

Sinónimos:

DOPAC, Homoprotocatechuic acid

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1 G
US$ 59,60
5 G
US$ 274,00

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1 G
US$ 59,60
5 G
US$ 274,00

About This Item

Fórmula lineal:
(HO)2C6H3CH2CO2H
Número de CAS:
102-32-9
Peso molecular:
168.15
Beilstein:
2211017
Número CE:
203-024-1
Número MDL:
MFCD00004338
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
24888293
NACRES:
NA.22

US$ 59,60

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Ensayo

98%

Formulario

powder

mp

127-130 °C (lit.)

solubilidad

water: soluble 50 mg/mL, clear, almost colorless

grupo funcional

carboxylic acid

cadena SMILES

OC(=O)Cc1ccc(O)c(O)c1

InChI

1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

Clave InChI

CFFZDZCDUFSOFZ-UHFFFAOYSA-N

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Descripción general

3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue.[1] A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described.[1] It is major metabolite of dopamine (DA).[2] The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs).[3] Semi-automatic fluorometric assay technique for DOPAC has been reported.[4]

Aplicación

3,4-Dihydroxyphenylacetic acid may be employed as ligand in the preparation of Mo(VI) complexes.[5]

Otras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCD4129
BCBL7919V
1451791V
1451791
1364209

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B H Westerink et al.
European journal of pharmacology, 38(2), 281-291 (1976-08-01)
A concurrent semi-automatic fluorometric assay technique for 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), is described. The method is based on a rapid manually performed isolation of DOPAC and HVA on small columns of Sephadex G-10 followed by an automated
A Y Deutch et al.
Brain research, 333(1), 143-146 (1985-04-29)
The effects of stress on dopamine (DA) metabolism in the mesencephalic DA cell body areas and DA terminal field regions were examined. Both mild footshock stress and exposure to a neutral stimulus previously paired with footshock resulted in a selective
Muhammed Saif et al.
Behavioural brain research, 243, 294-299 (2013-01-30)
Zebrafish are gaining popularity in behavioural brain research as this species combines practical simplicity with system complexity. The dopaminergic system has been thoroughly investigated using mammals. Dopamine plays important roles in motor function and reward. Zebrafish have dopamine receptors homologous
Electrocatalytic oxidation of 3, 4-dihydroxyphenylacetic acid at a glassy carbon electrode modified with single-wall carbon nanotubes.
Wang J, et al.
Electrochimica Acta, 47(4), 651-657 (2001)
Molybdenum catecholates as models for Mo in biological systems. 1. Synthesis and spectroscopic study on Mo complexes with 3, 4-dihydroxybenzoic and 3, 4-dihydroxyphenylacetic acid.
Karaliota A, et al.
Journal of Inorganic Biochemistry, 69(1), 79-90 (1998)
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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Can it be stored at -20C

    1 answer

    1. This product is stored at room temperature. In general, powder materials are not affected by freezer storage, however, this item has not been tested under these storage conditions.

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