This product is stored at room temperature. In general, powder materials are not affected by freezer storage, however, this item has not been tested under these storage conditions.
850217
3,4-Dihydroxyphenylacetic acid
98%
Sinónimos:
DOPAC, Homoprotocatechuic acid
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1 G
US$ 59,60
5 G
US$ 274,00
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1 G
US$ 59,60
5 G
US$ 274,00
About This Item
Fórmula lineal:
(HO)2C6H3CH2CO2H
Número de CAS:
Peso molecular:
168.15
Beilstein/REAXYS Number:
2211017
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
form
powder
mp
127-130 °C (lit.)
solubility
water: soluble 50 mg/mL, clear, almost colorless
functional group
carboxylic acid
SMILES string
OC(=O)Cc1ccc(O)c(O)c1
InChI
1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChI key
CFFZDZCDUFSOFZ-UHFFFAOYSA-N
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General description
3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue.[1] A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described.[1] It is major metabolite of dopamine (DA).[2] The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs).[3] Semi-automatic fluorometric assay technique for DOPAC has been reported.[4]
Application
3,4-Dihydroxyphenylacetic acid may be employed as ligand in the preparation of Mo(VI) complexes.[5]
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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B H Westerink et al.
European journal of pharmacology, 38(2), 281-291 (1976-08-01)
A concurrent semi-automatic fluorometric assay technique for 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), is described. The method is based on a rapid manually performed isolation of DOPAC and HVA on small columns of Sephadex G-10 followed by an automated
Simultaneous mass fragmentographic determination of 3, 4-dihydroxyphenylacetic acid and 4 hydroxy-3-methoxyphenylacetic acid in brain tissue.
F A Wiesel et al.
Journal of neural transmission, 35(4), 319-326 (1974-01-01)
A Y Deutch et al.
Brain research, 333(1), 143-146 (1985-04-29)
The effects of stress on dopamine (DA) metabolism in the mesencephalic DA cell body areas and DA terminal field regions were examined. Both mild footshock stress and exposure to a neutral stimulus previously paired with footshock resulted in a selective
Muhammed Saif et al.
Behavioural brain research, 243, 294-299 (2013-01-30)
Zebrafish are gaining popularity in behavioural brain research as this species combines practical simplicity with system complexity. The dopaminergic system has been thoroughly investigated using mammals. Dopamine plays important roles in motor function and reward. Zebrafish have dopamine receptors homologous
Molybdenum catecholates as models for Mo in biological systems. 1. Synthesis and spectroscopic study on Mo complexes with 3, 4-dihydroxybenzoic and 3, 4-dihydroxyphenylacetic acid.
Karaliota A, et al.
Journal of Inorganic Biochemistry, 69(1), 79-90 (1998)
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