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490709

Sigma-Aldrich

Sodium pyruvate-1-13C

99 atom % 13C

Sinónimos:

Pyruvic acid-1-13C sodium salt

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About This Item

Fórmula lineal:
CH3CO13CO2Na
Número de CAS:
87976-71-4
Peso molecular:
111.04
MDL number:
MFCD00084079
UNSPSC Code:
12352106
PubChem Substance ID:
24872592
NACRES:
NA.12

isotopic purity

99 atom % 13C

form

solid

technique(s)

mass spectrometry (MS): suitable

mp

>300 °C (lit.)

mass shift

M+1

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)[13C]([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i3+1;

InChI key

DAEPDZWVDSPTHF-FJUFCODESA-M

Application

Sodium pyruvate-1-13C results in sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Intravenous administration of hyperpolarized [13C]pyruvate enables real-time detection of metabolism by magnetic resonance spectroscopic imaging (MRSI). It is used as a precursor in estimating many volatile organic compounds for use in studying terrestrial biosphere.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Wissam Iali et al.
Angewandte Chemie (International ed. in English), 58(30), 10271-10275 (2019-05-23)
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Here, we communicate how signal amplification by reversible exchange (SABRE)
Kolby J Jardine et al.
Environmental science & technology, 44(7), 2454-2460 (2010-03-10)
Pyruvic acid, central to leaf carbon metabolism, is a precursor of many volatile organic compounds (VOCs) that impact air quality and climate. Although the pathways involved in the production of isoprenoids are well-known, those of several oxygenated VOCs remain uncertain.
Maria J Gonzalez-Rellan et al.
Nature communications, 12(1), 5068-5068 (2021-08-22)
p53 regulates several signaling pathways to maintain the metabolic homeostasis of cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes cellular metabolic stress, and we hypothesized that p53 could be linked to glucose maintenance. We
Jun Zhao et al.
Cell metabolism, 31(5), 937-955 (2020-04-24)
Cell proliferation and inflammation are two metabolically demanding biological processes. How these competing processes are selectively executed in the same cell remains unknown. Here, we report that the enzyme carbamoyl-phosphate synthetase, aspartyl transcarbamoylase, and dihydroorotase (CAD) deamidates the RelA subunit

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