391468

4-Hydroxypiperidine hydrochloride

98%

• Sinónimos: 4-Piperidinol hydrochloride
• Fórmula empírica (notación de Hill): C₅H₁₁NO · HCl
• Número de CAS: 5382-17-2
• Peso molecular: 137.61
• Beilstein/REAXYS Number: 3908995
• EC Number: 226-374-7
• MDL number: MFCD00035298
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864381
• NACRES: NA.22

Propiedades

• assay: 98%
• mp: 155-157 °C (lit.)
• solubility: methanol: soluble 25 mg/mL, clear, colorless
• functional group: hydroxyl
• SMILES string: Cl[H].OC1CCNCC1
• InChI: 1S/C5H11NO.ClH/c7-5-1-3-6-4-2-5;/h5-7H,1-4H2;1H
• InChI key: VKCORPXOKYDINR-UHFFFAOYSA-N

Descripción

General description

4-Hydroxypiperidine hydrochloride is a piperidine derivative. The synthesis of 4-hydroxypiperidine has been reported. 4-Hydroxypiperidine participates in the synthesis of 4-(4′-hydroxypiperidino)-4-phenylcyclohexanol and 1-(4-hydroxypiperidino)cyclohexanecarbonitrile. 4-Hydroxypiperidine is the starting material for the synthesis of Sibrafiban and Lamifiban, two non-peptidefibrinogen receptor.

Application

4-Hydroxypiperidine hydrochloride is suitable for use in the Ugi-multi component reaction (MCR) to study the use of miniaturised-synthesis and Total Analysis System (mSYNTAS) in solution phase synthesis and on-line analysis of Ugi-MCRs. It may be used in the synthesis of acetic acid-piperidine-4-yl ester.

Reactant for synthesis of:
14C-labeled E4010
PET tracer for imaging brain acetylcholinesterase

Reactant for allosteric modulators of metabotropic glutamate receptor subtype 5

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves