282227

Chlorhexidine

≥99.5%

• Sinónimos: 1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
• Fórmula lineal: [-(CH₂)₃NHC(=NH)NHC(=NH)NHC₆H₄Cl]₂
• Número de CAS: 55-56-1
• Peso molecular: 505.45
• Beilstein/REAXYS Number: 2826432
• EC Number: 200-238-7
• MDL number: MFCD00009673
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857031
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: ≥99.5%
• form: powder
• impurities: <1.0% water
• mp: 134-136 °C (lit.)
• solubility: water: soluble 0.08% at 20 °C
• functional group: amine; chloro
• SMILES string: Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
• InChI: 1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
• InChI key: GHXZTYHSJHQHIJ-UHFFFAOYSA-N

Descripción

General description

Effect of the chlorhexidine:hydroxypropyl-β-cyclodextrin inclusion compound on in vitro slabs of bovine dentine has been investigated[1].

Chlorhexidine is a cationic surfactant with broad-spectrum antimicrobial activity. It is used as a disinfectant in periodontal therapy and surgical scrubs.[2]

Application

Chlorhexidine, the "gold standard" in oral antiseptics, has been used to optimize novel slow release chlorhexidine coatings based on fatty acids in surgical sutures[3]. Chlorhexidine, antibacterial agent, has been used in preparaing chlorhexidine-functionalized calcium phosphate nanoparticles, useful for oral hygiene and dental treatment[4].

Información de seguridad

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H318,H410
• pcodes: P273 - P280 - P305 + P351 + P338 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves