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219223

Sigma-Aldrich

N,N-Dimethyl-1,3-phenylenediamine dihydrochloride

99%

Sinónimos:

3-(Dimethylamino)aniline dihydrochloride, 3-Amino-N,N-dimethylaniline dihydrochloride, N,N-Dimethyl-m-phenylenediamine dihydrochloride

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About This Item

Fórmula lineal:
(CH3)2NC6H4NH2·2HCl
Número de CAS:
3575-32-4
Peso molecular:
209.12
Beilstein/REAXYS Number:
3694384
EC Number:
222-693-0
MDL number:
MFCD00012971
UNSPSC Code:
12352100
PubChem Substance ID:
24853115
NACRES:
NA.22

assay

99%

mp

217 °C (dec.) (lit.)

solubility

water: soluble 100mg/2ml, clear to slightly hazy (faintly yellow to tan to purple)

functional group

amine

SMILES string

Cl.Cl.CN(C)c1cccc(N)c1

InChI

1S/C8H12N2.2ClH/c1-10(2)8-5-3-4-7(9)6-8;;/h3-6H,9H2,1-2H3;2*1H

InChI key

BZJPIQKDEGXVFG-UHFFFAOYSA-N

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Application

N,N-Dimethyl-1,3-phenylenediamine dihydrochloride (3-Amino-N,N-dimethylaniline dihydrochloride) was used in the preparation of a dimethylamino-aniline derivative.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
SHBJ8354
SHBB1247V
90996DJV
90996DJ
11822AH

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H Munakata et al.
The Tohoku journal of experimental medicine, 145(3), 251-257 (1985-03-01)
The high-iron diamine staining (HID), which has been used in histochemistry to stain sulfated glycoconjugates (SGC), was tested for detectability of authentic acidic substances (chondroitin sulfates A plus C, dermatan sulfate, heparan sulfate, chondroitin, hyaluronic acid, alpha 1-acid glycoprotein and
Paul W Manley et al.
Bioorganic & medicinal chemistry letters, 14(23), 5793-5797 (2004-10-27)
The constitutively active Abl kinase activity of the Bcr-Abl oncoprotein is causative for chronic myelogenous leukemia. Urea derivatives, structurally related to the therapeutic agent STI571, have been identified, which potently inhibit the tyrosine kinase activity of recombinant Abl. In particular
Juliane Rieger et al.
European journal of histochemistry : EJH, 63(2) (2019-06-25)
Mucins are of great interest in intestinal research and histochemical methods are often employed to identify them. Since it is in the nature of mucins that they are "hard to hold onto" once they come into contact with water, a
J Khosla et al.
American journal of respiratory cell and molecular biology, 10(4), 462-469 (1994-04-01)
The purpose of this study was to determine whether the cytochemically defined distribution of sulfated macromolecules is significantly different in microdomains of basement membranes (BMs) associated with different levels of pulmonary airways. The high iron diamine-thiocarbohydrazide-silver proteinate (HID-TCH-SP) technique, which
Ran Wang et al.
Bio-protocol, 7(14), e2394-e2394 (2017-07-20)
Specialized secretory cells known as goblet cells in the intestine and respiratory epithelium are responsible for the secretion of mucins. Mucins are large heavily glycosylated proteins and typically have a molecular mass higher than 106 Da. These large proteins are
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